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These include people with inherited metabolic disorders, severe malnutrition, kidney disease requiring dialysis, liver disease, or gastrointestinal conditions that reduce nutrient absorption

In 2023, 1 in 5 women and 1 in 4 men had hypertension, which gives about 1.28 billion people 1

The non-enzymatic components include the major cellular redox buffers: ascorbate (AsA) and glutathione (-glutamyl-cysteinyl-glycine, GSH) as well as tocopherol, flavonoids, alkaloids, and carotenoids (Arora et al., 2000

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The mechanism behind these patterns is a synthetic tetrapeptide acting on pineal gland function and on telomere-related cellular pathways