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Indeed, unlike other thiols, homocysteine incubation with endothelial cells induces an increased expression of the stress protein GRP78 and a decreased expression of glutathione peroxidase, a major intracellular antioxidant enzyme, through a mechanism that depends on an alteration of the intracellular redox potential (Kokame et al, 1996

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In the present study also, using SDS-PAGE and immunofluorescence microscopy, we have confirmed the increased expression of GSTA4-4 in GSH-depleted cells treated with ASA

Inset , raw anisotropy as a function of time following addition of SqrR first (up-arrow) and then 1 mM IAM (down-arrow) to free DNA