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As discussed in the preceding article, mtDNA lacks histone buffer proteins and lies in close proximity to the ROS-producing respiratory chain, so it depends on external protective molecules

Table 2 Application of probiotics in animal studies

Ochratoxin A induces oxidative DNA damage in liver and kidney after oral dosing to rats

It has been shown that, following type IV pili-mediated contact, the pilE gene encoding the major pilin and the genes for capsule synthesis are downregulated, and this is thought to allow for more intimate adhesion through other outer membrane adhesins

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