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Incubation of mouse primary hepatocytes in Met or 3-MTP induced a decrease of the GSH level and cellular damage (53)

It targets not just one, but several core mechanisms of aging simultaneously: telomere maintenance, epigenetic regulation, oxidative stress resilience, immune recalibration, and circadian rhythm restoration [1]

^ Partition and turnover of glutathione reductase from Saccharomyces cerevisiae: a proteomic approach (PDF)

10.1111/j.1582-4934.2008.00463.x

Moreover, signs of excess ROS are associated with the pathophysiology of other neurodegenerative diseases, such as Alzheimer's, or disorders affecting motor functional disturbances such as Amyotrophic Lateral Sclerosis or Huntington's disease 23