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Solid-phase peptide synthesis dominates the industry, but newer recombinant production methods can reduce costs for certain peptides

Because of the risk of serious adverse outcomes resulting from sedation and dissociation and respiratory depression caused by esketamine nasal spray administration, and the potential for abuse and misuse of the product, it is only available through a restricted distribution system under a Risk Evaluation and Mitigation Strategy (REMS)

Never freeze reconstituted peptides ice crystals damage peptide structure

To be more stable and safe, store the reconstituted peptide at a refrigerated temperature

They include minimal water retention and irritation at the injection site