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Deviations from this scheme are possible

In our in vivo studies with Tg2576 mice, we found that stereotactic delivery of adenoviral-Fbx2 to the brain significantly increased Fbx2 expression and decreased synaptic deficits coinciding with a reduction of BACE1, which is essential for A formation (Gong et al., 2010, 2013b)

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This synthesis addresses the need for a concise summary of dispersed data and clarifies which nutrients demonstrate robust clinical and mechanistic support for their role in depression intervention via gut microbiota modulation, and which require further investigation

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