Thyroid hormones exhibit profound metabolic effects characterized by an increased rate of both catabolic and anabolic reactions, resulting in an overall acceleration of the basal metabolism which is associated with increased oxygen consumption, respiratory rate, energy expenditure, and heat production (56)
Xie, N., Zhang, L., Gao, W
However, there are general scenarios where a provider might suggest a temporary pause: Severe Vomiting or Diarrhea: If you cannot keep fluids down, adding a medication that slows digestion may worsen the situation and lead to a hospital visit for IV fluids
Instead, microdosing is considered an off-label practice
It's worth noting, though, that any form of weight loss causes muscle loss, not just the kind that comes with weight loss drugs