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Myofibroblasts, the key effector cells in fibrosis, arise from fibroblasts, pericytes, endothelial cells, or epithelial cells via epithelialmesenchymal transition (EMT) under stimulation by transforming growth factor (TGF) -, clotting factors, and mechanical stress [11, 29, 34, 36]
(A) Aggregated results of 49 murine scRNAseq datasets showing expression of genes for canonical melatonin receptors, melatonin synthesis, and the NRF2-Glutathione pathway
Alba et al
3 Preclinical studies of Apigenin 3.1 Cardioprotective properties Celery, chamomile, lemon, papaya, guava, etc
Notably, GPX4 activity is affected by glutathione (GSH) and the trace element selenium (3)
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