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Headache: The most commonly reported adverse event was headache, characterized as mild to moderate in severity

Seek medical advice if you experience: Persistent headaches Heart palpitations Severe digestive symptoms Skin reactions after B12 injections Unusually high blood test results Are Vitamin B12 Injections Safe

Exact dosing varies by experimental design and species but generally follows preclinical trial standards for NNMT inhibitors

Tap a common dose or type your own

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)