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As nonsense mutations had never been reported before, it was postulated that nonsense mutations resulted in a complete loss of G6PD enzyme and this would be embryonic lethal
Biol Chem 378:793802 Crack PJ, Taylor JM, Flentjar NJ, de Haan J, Hertzog P, Iannello RC, Kola I (2001) Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury
10.1111/j.1471-4159.2007.04837.x 33 FarooqueU.OkorieN.KatariaS.ShahS
Beta Thalassemia is caused by a mutation in the HBB gene
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