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It had actually failed to impale his body in any way, and yet the view, the perception of that nail entering his boot at one end, and exiting the boot at the other was sufficient to create the experience of a nail that had gone through his foot

A study of associations between plasma metformin concentration, lactic acidosis, and mortality in an emergency hospitalization context

This does not necessarily mean that these medications do not have a place in the management of the condition, however

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Although it is recognised that LBP is a multifactorial condition, 40% of cases affected have been associated with degeneration of the IVD [66]