Studies of efinopegdutide, another dual GLP-1/GCGR agonist, have shown preliminary efficacy
Chest pain, shortness of breath, or rapid heart rate : which could indicate cardiovascular complications Severe weakness or inability to perform normal activities : suggesting possible electrolyte imbalances or other serious conditions You should also schedule a non-urgent appointment if you notice unintentional excessive weight loss (more than 23 pounds per week consistently), difficulty maintaining adequate nutrition , or new symptoms such as cold intolerance, hair loss, or mood changes that might suggest thyroid dysfunction or other endocrine issues
If you want to understand the medication journey from start to finish, this guide to getting GLP-1 prescribed explains the process clearly
Commonly reported issues include: Gastrointestinal Distress: Nausea, vomiting, and diarrhea are common, particularly when starting the medication
Starting conversations with your provider should include discussion of your weight-loss history, metabolic markers, family history of obesity or diabetes, and any prior experience with medications that affect appetite or mood