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The interpretation has been debated

Plant GPXLs, containing cysteine in their active site domain, may have dual roles, acting as glutathione peroxidase and thioredoxin peroxidase functions ( 2 O 2 and organic hydroperoxides, as well as their involvement in regulating cellular redox homeostasis by maintaining thiol/disulfide or NADPH/NADP+ ratios ( Deficiency in the activity of either GSH1 or GSH2 impairs GSH production, negatively impacting plant growth and development

doi: 10.1001/jama.2021.1831 11 JastreboffAMAronneLJAhmadNNWhartonSConneryLAlvesBet al

The interpretation should include methionine, SAM, SAH, homocysteine, the SAM/SAH ratio, symptoms, whole-blood histamine, zinc status, kidney function, mitochondrial energy, creatine demand, antioxidant reserve and toxic burden

[PubMed: 12771001] 742