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Diabetologia (2015) 58(11):258291.10.1007/s00125-015-3728-z 5 HareKJKnopFKAsmarMMadsbadSDeaconCFHolstJJet alPreserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

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While existing animal models, which replicate specific phenotypes by targeting individual organ systems, offer the closest approximation to the HFpEF pathology, they still fall short of fully recapitulating the human condition

The integrity of the BBB model was tested by permeability assays for SF and albumin marker molecules

Ethics statement The studies involving humans were approved by Ethics Committee of Beijing Anzhen Hospital of the Capital University of Medical Sciences