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In acute liver injury, ammonia concentrations greater than 200 mol/L are associated with cerebral edema and a poor prognosis, 83 and it has been suggested that ammonia concentrations should be used as part of the evaluation of prognosis in acute liver failure

Components of the remethylation reactions require various vitamins to complete the reaction

This is more likely to occur when starting GlyNAC supplementation or when increasing the dosage rapidly

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