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reported that GLS-driven Gln metabolism is a regulator of radiotherapy tolerance in prostate cancer (PCa) and that high expression of GLS 1 and c-MYC, key regulators of Gln, are significantly associated with reduced progression-free survival in prostate cancer patients treated with radiotherapy

PMID: 121 BallaATranBValtariAStevenPScarpelliniCAugustynsKet al

The findings have been cited by dozens of subsequent studies, including the 2018 Pickart & Margolina review of GHK-Cu regeneration science and the 2025 Kuceki study combining copper peptides with microneedling

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From clinical measures, it was only anxiety, as measured with HARS, that was significantly elevated in K2 relatively to K1