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Phase 2 trial results, published in 2023 in the New England Journal of Medicine (Jastreboff et al., NEJM 2023), demonstrated that participants receiving the highest dose of retatrutide lost an average of approximately 24% of their body weight over 48 weeks a finding that attracted considerable attention from the medical and scientific communities

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Understanding the Revolution: Wegovy and Zepbound For many years, effective medical interventions for chronic weight management were limited

However, this doesn't mean evening injections are unsafemillions of GLP-1 users follow evening schedules without sleep disruption