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The most commonly reported effects include: Mild water retention during the first 2 to 4 weeks Occasional headaches, particularly at treatment initiation Redness or irritation at the injection site Tingling or numbness in the extremities Short term fatigue or flushing after injection Ipamorelins selectivity provides a meaningful safety advantage

The lactone moieties of AFB1 are thought to be important for its toxicity as cleavage of the lactone ring in AFB1 resulted in the loss of fluorescence and its mutagenicity and toxicity are reduced by 450- and 18-times, respectively (Lee et al., 1981)

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