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The cherry on top is that neither of them can currently produce enough medicine to meet the demand

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Nausea, vomiting, and diarrhea are common during dose escalation

Am J Physiol Gastrointest Liver Physiol (2007) 292(5):G136675.10.1152/ajpgi.00516.2006 22 OyaMKitaguchiTPaisRReimannFGribbleFTsuboiT

This common plateau occurs when weight loss abruptly slows down or stops completely, leading patients to mistakenly believe the medication is no longer effective anymore