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Waters Corporation, MA) using water with 0.1% formic acid (0.1% methanol and 5 mM ammonium acetate) detected with a Xevo-G2-QTOF MS (Waters Corporation) operating in a positive mode

NRF2 is a transcription factor that governs the antioxidant pathway by targeting GSH metabolism-related genes 41,49

Liposomal delivery systems were originally developed to optimize the pharmacokinetics and efficacy of pharmaceutical drugs

Convento M, Pessoa E, Aragao A, Schor N, Borges F (2019) Oxalate induces type II epithelial to mesenchymal transition (EMT) in inner medullary collecting duct cells (IMCD) in vitro and stimulate the expression of osteogenic and fibrotic markers in kidney medulla in vivo

It is formulated with a proprietary blend of sea buckhorn and macadamia oil, which provide antioxidant support and reduce inflammation