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Dampaknya, warna kulit bisa terlihat lebih merata, noda hitam perlahan memudar, dan kulit kelihatan lebih cerah sehat, bukan putih pucat

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33 Ultimately, these factors may adversely affect treatment efficacy and lead to higher rates of relapse in patients receiving conventional isotretinoin for treatment of AV

This dangerous combination can rapidly precipitate acute heart failure, fatal pulmonary edema, cardiac arrest, and death (Ebert 2026, Medical Advisory Board 2026a, Medical Advisory Board 2026b)

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