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These medications are remarkable, Hardaway said

J., 96, e70102, 2025

Statistical analysis The planned sample size of 495 participants was estimated to provide over 80% statistical power to detect a difference between any active treatment group and placebo with respect to the primary endpoint using a two-sided t -test with significance level of 0.05

This decision must be individualized based on response, side effects, and clinical judgment

Compared with in the H/R + semaglutide group, the protein expression levels of Parkin and PINK1 were significantly higher in the rapamycin group, whereas they were significantly reduced in the 3-MA group