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There are 3 main factors that make weight loss more difficult with PCOS: 1

Current Canadian pricing for established GLP-1 medications remains substantial: Mounjaro: Approximately $300-400 monthly depending on dose Zepbound: Similar pricing structure to Mounjaro Ozempic: $200-300 monthly across different strengths Wegovy: $400-500 monthly for maintenance doses Regulatory Pathway in Canada For Pfizer's long-acting GLP-1 drug to reach Canadian patients, the company must complete clinical trials and submit a New Drug Submission to Health Canada

Then, patients move to monthly maintenance doses to keep B12 levels steady over time

Studies show that genetic testing can spot PWS early

The additional pathway would be the direct modulatory effects microbes and metabolites have on the BBB itself, influencing the integrity of the brains primary defense mechanism and therefore impacting brain health