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Another important feature of Asians with diabetes is reduced insulin secretory function relative to increased insulin resistance [4]
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GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats
While directly measuring neuroprotection in living patients is technically unfeasible, alternative strategies, such as monitoring pro-inflammatory markers or neuroprotective cytokines in the plasma of patients receiving istradefylline, could offer valuable mechanistic insights and serve as surrogate indicators of therapeutic activity [485]
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