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Over the past decade, new tools such as high-sensitivity biomarkers, coronary calcium scoring, and advanced imaging technologies have emerged, helping to detect risks earlier and tailor interventions more accurately

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BarbatoVTaleviRBraunSMerollaASudhakaranSLongobardiSet al

Semaglutide, which acts on GLP-1 receptors in the gut, has the potential to modulate this microenvironment

Similarly, metallic nanoparticles (MNPs) (gold, silver, zinc oxide) are conjugated with phytoextracts like Aloe barbadensis , Leucas aspera , Pyrenacantha grandiflora , and Withania somnifera for wide therapeutic efficacy against microbial infections, ulcerative colitis, cancer, and oxidative stress by facilitating extended drug circulation, intercellular targeting, drug stabilization, and higher delivery [19, 20]