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PradaMSaraivaMGarridoMVSrioATeixeiraALopesDet al
The decision to continue, adjust, or discontinue therapy should be based on objective body composition measurements (DEXA scans, circumference measurements), achievement of fat loss goals, tolerance and side effect profile, and physician assessment of metabolic markers
Our results show that senescent cells rely on GPX4 to prevent ferroptosis and that GPX4 inhibitors kill senescent cells
62 Moreover, small molecule inhibitors of LDHA, such as GSK2837808A, FX-11, galloflavin, and N-hydroxyindole-based compounds, inhibit pyruvate-to-lactate conversion, and may possess the potential to regulate lactylation
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