The goal is consistent: deposit the peptide in the subcutaneous fat layer, not in the dermis above or the muscle below
Although nanotherapy has many advantages, some problems remain: the complexity and heterogeneity of tumor biology lead to uncertainty about its efficacy, as the interaction of NPs with this biology is not yet clear, and challenges related to NP cost, chemical processes, manufacture, and control persist (172, 173)
Furthermore, excess GSSG is postulated to result in alteration of a variety of cell functions, including enzyme function, protein synthesis, cell integrity, microtubular function, transport processes, and release mechanisms
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