J Formos Med Assoc (2013) 112(3):14450
Key Functions of GLP-1 Simplified: Supports insulin release to regulate blood sugar levels
ROS/PI3K/Akt and Wnt/-catenin signalings activate HIF-1-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer
Using a shortest-paths analysis, we identified direct interactors within the cAMP, NF-B, AMPK, and adipocytokine/adiponectin pathways, along with proteins previously reported to modulate GLP1R function (-arrestin, CAV1, DPP4, RAMPs, NEP)
For instance, some Wnt molecules facilitate myogenesis during regeneration while others have been demonstrated to drive the differentiation of satellite cells into a fibrotic lineage [82, 83]