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The root cause needs to be found and treated

Methotrexate-polyglutamate stimulates pro-inflammatory cytokines, such as TNF-, IL-6, and nuclear factor- B (NF-B), initiating inflammatory reactions that damage hepatocytes

doi: 10.1016/j.cell.2024.05.013 357 SchauwvliegheA.RijndersB

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