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For pernicious anaemia without neurological involvement , the standard UK protocol recommended by NICE involves an initial loading phase followed by maintenance therapy
There are also cases where patients with low B12 levels have problems with fertility or are more likely to develop dementia
B12 shots for malabsorption or dietary restriction Vegans, vegetarians, older adults, and people with GI conditions (Crohn's disease, celiac disease, pernicious anemia) commonly have inadequate B12 absorption
For those who suffer from a vitamin B12 deficiency, injections will likely be recommended every 10 days as a build-up phase and then will continue as a monthly treatment or to be administered every 2 to 3 months in order to completely reverse the side effects of the deficiency