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May your metabolic health stay optimized, your weight management stay sustainable, and your supplement choices stay evidence-based.

The results of our studies reveal that bone marrowderived DPP-4 plays an unexpectedly important role in the lipid-lowering effects of DPP4i (Figure 11)

This has attracted attention because better blood flow can, in theory, help deliver oxygen and nutrients to injured tissue

Gupta M, Sharma V, Mahajan VK, Singh R

However, these studies typically involved healthy volunteers or individuals with prediabetes rather than patients already receiving GLP-1 receptor agonist therapy, limiting direct applicability to the clinical question of combination benefits