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Big Pharma is still piling in: Pfizer closed its 2023 $43B Seagen deal to expand its ADC platform, and PD-1 biosimilars are expected to arrive late-decade, expanding access rather than collapsing the category, as CRA Insights noted

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(2026) discuss the evaluation framework for acquired oral hyperpigmentation broadly, and smoking history would typically be part of any comprehensive clinical assessment of oral pigmentation

Both conditions involve degenerative changes to the tendons that attach forearm muscles to the bony prominences around the elbow joint

A 2024 randomised trial found IV glutathione reduced melanin by 18.7% over eight weeks, while oral glutathione at higher cumulative doses reduced melanin by only 3.2%