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How to Do a 48 Hour Fast Theres no right time of day to start a 48 hour fast, Fernando notes

Exendin-4 and liraglutide increased the number of osteoclast precursors in mice, while the addition of mature osteoclasts reduced the absorption area, suggesting that GLP-1RA promoted osteoclast differentiation but inhibited its absorptive activity

There is a lot of evidence to back it up, but as with anything like this, there are those who warn against it too

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