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10.1016/j.yexcr.2017.07.032 120 TakedaS.SatoN.Uchio-YamadaK.SawadaK.KuniedaT.TakeuchiD.et al (2010)

254,255 This may help couples to adapt to a child-free life or begin exploring the possibility of adoption

This is clinically significant for drugs with narrow therapeutic windows (thyroid hormone, anticoagulants, immunosuppressants)

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If compounding pharmacies are eventually authorized to produce these compounds, patients would need a physician's prescription, which would add a consultation cost but also provide some regulatory oversight