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Glutamate competitive and non-competitive ligands, binding to the same or to a different receptor site of the endogenous ligand, have been on development for at least three decades

The most common ones include: Nausea Vomiting Diarrhea or constipation Stomach pain Fatigue Most side effects are mild and improve over time

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To investigate the effect of hypocarnitinemia on MAD efficacy, we assessed the percentage change in the number of seizures between patients with low free carnitine and normal free carnitine for each follow up timepoint

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