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In the folate cycle, serine donates one-carbon unit to tetrahydrofolate (THF) to form 5,10-methylene-THF (5, 10-mTHF), which fuels DNA biosynthesis and generates 5-methyl-THF (5-mTHF) (Fig

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Therapeutic strategies Given the role of ferroptosis in the pathogenesis of testicular diseases, ferroptosis is a very promising therapeutic target for treating and preventing male reproductive diseases