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Amounts of metal were measured using an Agilent 7900 ICP-QMS in low-resolution mode, taking natural isotope distribution into account

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Our results demonstrate that the core clock protein BMAL1 regulates astrocyte activation and function in vivo, elucidating a novel mechanism by which the circadian clock could influence many aspects of brain function and neurologic disease.

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These processes contribute to ROS and RNS overproduction and oxidative stress which intensifies cytokine secretion in keratinocytes (163)