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Following subcutaneous administration of 420 mg REPATHA once monthly, mean trough serum concentrations were 22.4 mcg/mL and 25.8 mcg/mL over the Week 12 and Week 24 time points, respectively
34 However, in a placebo-controlled trial in 99 subjects with PCOS, 12 weeks of treatment with a synbiotic supplement providing the prebiotic inulin plus a combination of seven probiotic strains improved LDL- and high-density lipoprotein (HDL)-cholesterol levels, but did not alter triglyceride levels, body weight, or body composition
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3a), nor influenced glucose tolerance, insulin action, or glucose production (Supplementary Fig
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