Severe events that have been reported and contributed to discontinuation include IgE-mediated hypersensitivity in 4% of participants in some trials, with one reported anaphylaxis-like reaction [wong (2008) abstract]
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Evolutionarily conserved roles for blood-brain barrier xenobiotic transporters in endogenous steroid partitioning and behavior
De novo lipogenesis: Dysregulation in the acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase-1 resulted in hepatic steatosis and hypertriglyceridemia (Hong et al