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[20] [21] Seek urgent medical advice if you are already taking a GLP-1 medication and experience: Severe, persistent abdominal pain (possible pancreatitis) A new lump in your neck or changes in your voice Symptoms of severe hypoglycaemia (if taking other diabetes medications) Signs of thyroid dysfunction despite stable levothyroxine therapy Persistent vomiting leading to dehydration or inability to take oral medications Severe right upper abdominal pain, fever or jaundice (possible gallbladder disease) Open communication with your healthcare team ensures that treatment decisions are individualised, evidence-based, and aligned with your health priorities

These can be altered by other factors too- caloric restriction and exercise for starters

The comparison gets even more compelling over time

doi:10.1186/s40985-017-0077-0 McCance-Katz EF, Satterfield J

Your provider will help you consider your dosage, lifestyle, and alternative options