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Additionally, glutathione supports immune function by aiding in the activation and regulation of immune cells, contributing to a balanced immune response

These observations were further confirmed by Hoechst 33342 staining, which revealed extensive detachment of cells from the cell culture substratum and increases in apoptotic bodies of HepG2 cells incubated with H 2 O 2 and TNF for 16 h (Fig

Maintenance of intracellular ROS homeostasis ROS act as crucial signaling molecules at physiological concentrations, playing a crucial role in maintaining normal cellular functions

This highly sensitive and specific method allows us to precisely quantify both reduced glutathione (GSH) and oxidised glutathione (GSSG) from just a few drops of blood collected via a simple dried blood spot (DBS) card

This work will focus on 2D cell culture models (endothelial cell lines and primary ECs), 3D cell culture systems (scaffold-free and scaffold-based), and 3D cell culture models (such as organ-on-a-chip)