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Recent studies have shown that paternal diabetes significantly alters sperm epigenetic profilessuch as DNA methylation, histone modifications, and microRNA (miRNA) expressionpotentially increasing the susceptibility of offspring to metabolic disorders [93, 94]

Additionally, some patients reach their weight goals within 34 months, while others benefit from staying on the medication longer, often up to a year

The most frequently reported side effects, by percent, for GLP-1s, was reported by Liu and colleagues in the journal Frontiers in Endocrinology in December 2022

Side effects Both drugs have potential side effects that range from mild to serious

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