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This NAD+ elevation activates sirtuins, particularly SIRT1 in adipocytes and hepatocytes, which deacetylates and activates numerous metabolic regulatory proteins including PGC-1, a master regulator of mitochondrial biogenesis, oxidative metabolism, and thermogenesis
In fact, B12 shots can also improve our cognitive function, maintain our vision, and lower our risk for age-related conditions like osteoporosis, macular degeneration, and cardiovascular disease
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