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DISCUSSION Using a male DIO mouse model, we conducted a parallel comparison between different weight loss approaches, including VSG and semaglutide treatments, to evaluate their metabolic, skeletal, and cardiac outcomes

Endocrinologists viewed their ideal patient as an individual with established cardiovascular disease or high cardiovascular risk, including those with diabetic kidney disease, who are already being treated with more than one oral medication (including either SGLT2is or GLP1-RAs) and an HbA1c level exceeding the established target