These findings align with our results in the METH-PH mouse model and METH-treated PASMCs, confirming that macrophage-derived LCN2 is involved in promoting PASMC proliferation by inducing ferroptosis resistance, which could be a potential mechanism for METH-PAH in humans
Without significant increases in BrdU or Ki67 staining, neoplastic changes in the exocrine compartment would seem unlikely, although endocrine neoplasia would still seem to be a possibility
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29 , 40 Asimismo, los iSGLT2 tambin producen aumento del glucagn, gluconeognesis heptica 29 , 41 y riesgo de cetoacidosis euglucmica, efectos que podran contrarrestarse con los AGLP1, dando soporte fisiolgico a su combinacin
Andra Picincu, CN, CPT Medical Reviewer Andra Picincu is a certified nutritionist, personal trainer, and content writer with more than 15 years of experience