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The OFC and ventral striatum receive inputs from sensory cortices and calculate the reward values

However, in those with thickened or macerated areas of skin, topical retinoids, topical vitamin D analogs such as calciprotriol, or topical keratolytics such as ammonium lactate and salicylic acid are the primary treatments used for localized lesions (8-10)

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Both double mutants with F102A 3.33 /F190A 5.47 and F159A 4.64 /F190A 5.47 completely abolished activation by curcumin and LPI

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