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A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

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27:1265-1270 [PubMed: 15161773] 47

The Centers for Disease Control and Prevention (CDC) reports that more than 37 million Americans have diabetes, emphasizing the need for individualized therapies that improve glycemic control and long-term patient outcomes through precision-based drug interventions

Recently, several multi-targeting agonists of GIPR, GLP-1R, or GCGR for treating T2DM and obesity have been in clinical trials