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Decreasing estrogen levels diminish microbial diversity, notably resulting in a reduction of Firmicutes such as Clostridium (74)

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Treatment of STZ-induced diabetic rats with another DPP-4 inhibitor, vildagliptin (10 mg/kg), significantly reduced plasma TNF- concentration and decreased nitric oxide concentration in serum and pancreatic homogenates compared with untreated diabetic rats [46]

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