Fsp1 knockout enhanced CaOX-induced ferroptosis in MTECs To further investigate the role of Fsp1 in oxalate-induced AKI, the CRISPR-Cas9 system was employed to create Fsp1 knockout MTECs and confirmed through Sanger sequencing and Western blot analysis (Fig
Development and validation of response biomarkers would support evidence-based patient selection, optimizing outcomes while minimizing treatment of unlikely responders
For people living with type 2 diabetes, the benefits go beyond weight loss
Cristofori F, Dargenio VN, Dargenio C, Miniello VL, Barone M, Francavilla R
By using GHK-Cu as a single, well-characterized entity, researchers can evaluate both localized and systemic effects of copper peptide signaling without the confounding variability of mixed or poorly defined copper complexes