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Underlying mechanisms contributing to cardiovascular and renal protection are at least partially different between GLP-1RAs (mainly anti-atherogenic and vascular effects) and SGLT2is (mainly systemic and intrarenal hemodynamic changes)

In adults with normal renal function, the half-life in the initial phase averages 0.5 hours and the half-life in the terminal phase averages 10-20 hours (range: 7-39 hours)

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Anti-inflammatory and gut microbiota modulatory effect of lactobacillus rhamnosus strain ldtm 7511 in a dextran sulfate sodium-induced colitis murine model

Equine/animal-type melanoma in humans: malignant melanoma with prominent pigment synthesis Introduction The existence in horses of skin neoplasms comprising nodules of heavily melanized cells has been recognized for centuries and is termed equine melanotic disease